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Regimen Information

For CHOP, including Side Effects


For the treatment of Non-Hodgkin's Lymphoma

How CHOP chemotherapy is given and possible side effects.

CHOP for the treatment of Non-Hodgkin's Lymphoma

A chemotherapy regimen consisting of cyclophosphamide, hydroxydaunorubicin hydrochloride (doxorubicin hydrochloride), vincristine and prednisone used to treat both indolent and aggressive forms of non-Hodgkin lymphoma.

CHOP is the acronym for a chemotherapy regimen used in the treatment of non-hodgkin’s lymphoma.

Drugs in the CHOP combination:


= Cyclophosphamide


= Doxorubicin Hydrochloride (Hydroxydaunomycin)


= Vincristine Sulfate (Oncovin)


= Prednisone

Chemotherapy is often given as a combination of drugs. Combinations usually work better than single drugs because different drugs kill cancer cells in different ways.


  • Infection

  • Anemia

  • Nausea & Vomiting

  • Constipation

For more information, see the 'Expert Resources' tab below.

Community Responses

Often, the most helpful information regarding treatment side effects comes not from clinical brochures, but rather from other patients like you. We've collected the most helpful community resources to help you prepare for the side effects and coping tips for your chemotherapy regimen.

What side effects did you experience while on this medication?

Hi, I'm T Howard

Chop-non Hodgkins Lymphoma – acid reflux, sore throat, awful taste in my mouth, thrush, sore feet, bloating, weight gain, slight tingling in fingers and lots of fatigue.

  • Thu Jun 18, 2015
Hi, I'm Ronald B H.

Chop-non Hodgkin’s Lymphoma, Had issues with Thrush, sore throat, Weakness, no apatite, weight loss.

  • Mon Dec 8, 2014
I'm Susie, and I support someone with cancer

Chop- r non hodgkins follicular stage 4 grade 1- retaining fluid

  • Sat Aug 3, 2013

This discussion needs your voice!

What were the specific side effects that you experienced while taking this medication? How did you manage them?

What coping tips would you give to new patients on this regimen?

Hi, I'm Ronald B H.

Call your Doctor as soon as you seem symptomatic, they seem to have something for everything, and they work.

  • Mon Dec 8, 2014

This discussion needs your voice!

What do you wish you had known before taking this medication? What information would you like to pass on to patients who are beginning this medication?

Treatment Overview

This chemotherapy regimen is commonly used to treat:

Other chemotherapy regimens for the treatment of Non-Hodgkin's Lymphoma:

See Expert Resources

The Navigating Care Library includes articles about cancer, chemotherapy regimens and drugs from the the National Cancer Institute and other experts.

Specific Facts for Your Diagnosis

Learn about treatment options and managing side effects from experts.

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